Sensory Hyperreactivity and Chemical Sensitivity, Tilia
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Latest update: 2011-02-27

Research group

The research presented on this website was all performed as teamwork with colleagues and the staffs at the Asthma and Allergy Research Group, Department of Respiratory Medicine and Allergy, The Sahlgrenska Academy at Gothenburg University, Sweden and at the Allergy Centre, Central Hospital, Skövde, Sweden. Without their constant help and collaboration none of the presented results would be available today. The Departments have always supported this research and made it possible to perform scientific studies often demanding extensive resources. Especially I want to mention:

At the Department of Internal Medicine/Respiratory Medicine and Allergology, Sahlgrenska Academy, University of Gothenburg, Sweden:

Ewa Ternesten-Hasseus, RN, PhD, presented her thesis in 2006; "Airway sensitivity to chemicals and scents, symptoms, trigger factors, and the capsaicin inhalation test" a thorough and careful work in mapping patients with sensitivity to chemicals and scents and in many ways a pioneering work. The conclusions of her thesis are the following:

"In patients with SHR and MCS airway sensory reactivity is increased, suggesting that neurogenic factors may be of importance. Though the methacholine inhalation test may be of some value in assessing these patients, in that it can exclude the possibility of bronchial asthma, the capsaicin inhalation test seems to be a more useful diagnostic tool. In conducting capsaicin inhalation testing it is important to know the type of inhalation device used, particle size, airflow rate, and inspiratory flow rate, as these factors influence the strength of reaction. SHR appears to be a chronic condition; it is associated with reduced HRQL (health related quality of life) and the long-term persistence of increased capsaicin cough sensitivity."

Ylva Ekstrand, MD, will in a couple of years be a specialist in internal medicine and allergology. She has a special interest in the connection between asthma and SHR and is right now studying a group of well defined patients with asthma and if their sensitivity changes from treatment with inhaled steroids.

Ewa-Lena Johansson is a physiotherapist and since 2009 a doctoral student in the study of SHR. She has a special interest in exercise-induced symptoms in SHR and is also studying rib cage mobility in SHR.

Margareta Brandt-Gertmo, RN, takes care of time booking, scheduling and many provocations. She knows and remembers the patients and has an excellent knowledge within this field.


At the Allergy Centre, Central Hospital, Skövde, Sweden:

I have since several years, scientific collaboration with Mats Bende, professor, MD and Åke Johansson, MD, both enthusiastic researchers with great interest and understanding in non-allergic/non-asthmatic airway hyperreactivity. Anton Bohman, MD, will in a couple of years be a specialist in ENT- medicine and is also a doctoral student in SHR of the upper airways.

Christel Larsson, RN, research assistant is an outstanding co-worker who with great efficacy plan and organise different scientific studies.


At the Department of Psychology, Umeå University, Sweden:

Steven Nordin, professor, has the last years enriched and broadened our research in airway sensory hyperreactivity with psychological competence and never failing enthusiasm.

Linus Andersson is a doctoral student studying epidemiology and evoked brain potentials in SHR.


At the Department of Laboratory medicine, Lund University, Sweden:

For analyses of capsaicin receptors we cooperate with a research group in Lund: Professor Edward Högestätt, associate professor Peter Zygmunt and MD Lisa Alemyr.